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To avoid any inaccuracy in the colocalisation measurement, only few middle z-stacks (based on the number of stacks which can vary between images) where a clear nuclear rim shape was observed were chosen

Epidemiology Incidence [1] Detected in 0.24.5% of autopsies Detected in 0.52.3% of small bowel contrast studies More common in adults 40 years of age [2] Typically detected in the 6th or 7th decade of life [2] No definitive sex predilection [1] [2] Etiology [1] Acquired pseudodiverticula Intestinal dyskinesia or neuromuscular dysfunction leading to localized areas of increased pressure Herniation occurs at points of weakness in the muscularis layer, typically where vasa recta penetrate the bowel wall on the mesenteric border

Thats why we committed to a process of small-batch synthesis