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Estimated at 46 hours based on pharmacokinetic modeling

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Reductions of AST, ALT and -glutamyl transferase (-GT) were found in the PIO arm although the between-arm difference was only significant for -GT ( p = 0.024)

aeruginosa produces exotoxins (e.g., exotoxin A) that disrupt host cell function, leading to cell death and promoting the spread of infection [22]