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Abbreviations MNM: Micro/nano motor UC: Ulcerative colitis H

Results Eight thousand nine hundred ninety-one of the 17,598 participants randomized to pantoprazole/placebo (51%) had eGFR recorded at baseline and open-label extension enrollment and were included in the rate of eGFR change population (mean age 67 [SD 8] years, 22% female, mean baseline eGFR 75 [SD 17.5] ml/min per 1.73 m 2 )

Altered Zn influx, efflux or buffering leads to intracellular zinc imbalance, which disrupts core molecular processes, including enzymatic activity, protein folding, signaling pathways and redox homeostasis

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To strengthen the studys validity, it would be beneficial to assess factors such as CPT I, the key enzyme controlling the mitochondrial transportation of long-chain fatty acids, OCTN2, the carnitine transporter gene, AMPK, and malonyl-CoA