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Our identification of VRK2-mediated SLC7A11 trafficking suggests a potential immune evasion mechanism, as SLC7A11-high tumors often display T cell exclusion phenotypes [37], warranting future investigation into whether VRK2 expression could predict therapeutic response to combined ferroptosis inducers and immune checkpoint inhibitors

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524,525 Pancreatic cancer Researchers first compared the expression of GLP-1R in human pancreatic cancer tissues with adjacent non-tumorous pancreatic tissues, finding generally lower or absent expression of GLP-1R in pancreatic cancer tissues