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Topical application uses 1-2% concentration in serums applied daily

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338 For individuals with MDD, it is necessary not only to increase the frequency of social contact but also to improve self-awareness and foster close functional supporttive relationships

56, 158, 159 However, so far controversial results have been reported regarding its effect on blood pressure, depending on the species and the experimental conditions, and it is therefore difficult to predict the effects of long-term AT 2 receptor stimulation in human beings

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