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GLP-1 Medications and Gallbladder Risk in Patients Who Still Have One For patients with an intact gallbladder, some observational data suggests that rapid weight loss from GLP-1 therapy may increase the risk of gallstone formation, particularly during the initial weeks of treatment

Days to months: Delayed generalized rashes or new persistent dermatitis may appear and are harder to attribute immediately to the drug

Mast cells are innate immune cells that release inflammatory mediators, including histamine, when they detect a threat

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This appears linked to BPC-157s influence on the gut-brain axis