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No statistical method was used to predetermine sample size

A key mediator of the beneficial effect of weight loss on insulin sensitivity is the loss of ectopic fat [11], which is highly correlated to insulin resistance and T2DM [1113]

Micevic G, Muthusamy V, Damsky W, Theodosakis N, Liu X, Meeth K et al

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Both groups specifically called out that while aerobic exercise has cardiovascular benefits and supports overall health, it does not provide sufficient mechanical stimulus to prevent muscle breakdown when the body is in a caloric deficit