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The viral hijack of human ACE2 receptor disrupts RAAS activation, upregulates NF-B pathway, triggers cytokine storm, hypertension, cell proliferation, inflammation, and fibrosis, where all elicit detrimental effects on every bodily organ during SARS-CoV-2 infection 635
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This reality is often overlooked in society, and it has been a personal mission of mine to advocate for those who face these challenges
Though similar studies on severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) have not yet been performed, due to existing similarities in these pathogens and the immunological response they trigger, recent studies have suggested that G6PD deficiency may potentially impact the prognosis, clinical outcomes, and severity of SARS-CoV-2 infection
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