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This review summarizes the function of insulin in glucose metabolism in metabolic tissues, such as liver, skeletal muscle, and adipose tissue, and describes several putative mechanisms of insulin resistance, including the ectopic accumulation of lipids in liver and skeletal muscle

(2) incomplete control of confounding factors (comorbidities, concomitant medications)

[22] reported different expression of GLP-1R in non-tumorous thyroid tissue according to inflammation status

In this context, Once monthly pipeline remains in clinical trials, pivotal efficacy data is lacking at this stage