It's usually not dramatic enough to be the primary reason for using the peptide (Adan et al., 2006)
Studies in rats show ipamorelin increases tibial and vertebral BMC, primarily through bone growth and increased dimensions, while maintaining volumetric bone mineral density (BMD) (5)
Less common but serious risks include pancreatitis, gallbladder disease (including gallstones), acute kidney injury (usually secondary to dehydration), and a possible increased risk of medullary thyroid carcinoma, which has been observed in rodent studies but not confirmed in humans
doi: 10.1021/acschemneuro.6b00207 Summary Keywords CRISPR/Cas9, dopaminergic pathways, gallium nanoparticles, neurodegenerative, neuroglia, Parkinsons Citation Yadav VK, Dhanasekaran S, Choudhary N, Nathiya D, Thakur V, Gupta R, Pramanik S, Kumar P, Gupta N and Patel A (2025) Recent advances in nanotechnology for Parkinsons disease: diagnosis, treatment, and future perspectives
Using it regularly may also help with glutathione skin whitening and make your complexion look better