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In rare cases, very high doses have been linked to liver abnormalities

Studies have found that KA induces ERS through G protein inwardly rectifying K + receptor, activates ATF6, glucose-regulated protein 78 and IRE1, and stimulates the expression of pyrin domain-containing protein 3 (NLRP3) and NF-B [111]

Respirology 21 , 427437 (2016)

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