These findings position GLP-1RAs as a potential fourth pillar of kidney-protective therapy in diabetes, alongside renin-angiotensin system inhibitors (RASi), SGLT2i, and finerenone, and suggest a shift toward rapid initiation of combination therapies for maximum kidney protection

discuss any supplement use with your clinical team If you are taking other prescribed medicines , particularly those with a narrow therapeutic index, as delayed gastric emptying associated with GLP-1 therapies may affect their absorption Seek urgent medical attention contact NHS 111 or go to an urgent care centre if you experience any of the following whilst taking a GLP-1-based medicine: Severe or persistent abdominal pain (which may rarely indicate pancreatitis or gallbladder disease) Persistent vomiting or inability to keep fluids down, which can lead to dehydration Symptoms of hypoglycaemia (shakiness, sweating, confusion, or palpitations), particularly if you are also taking insulin or a sulfonylurea A pharmacist is an accessible first point of contact for supplement-related queries and can advise on potential interactions, product quality, and appropriate dosing

After losing over 19 pounds, 14.3 inches (11.6 off waist) on GLP-1, and increasing lean mass 3% a client came to us at a crossroads
However, when you are dehydrated, your liver has to work harder to process the alcohol because there is less water available to help flush out toxins
V Margaritelis, A