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Obesity has become a major global health crisis impacting every corner of the world, with some of the most rapid increases in prevalence seen in low- and middle-income countries

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We find that GLP-1R agonism enhances membrane expression of DAT

Summarizing most of the studies to date, the rates suggested a two- to tenfold increase in NAION in patients with type 2 diabetes taking semaglutide, and the risk increased only between 2 and 4 years of treatment