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Two trials were conducted to investigate the effects of oral semaglutide on the pharmacokinetics (PK) of four cardiovascular and glucose-lowering medications with different solubilities and permeabilities based on the Biopharmaceutics Classification System (BCS) [8]

In contrast, when cells had been pretreated with BSO before AX addition, a drastic decrease in both GSH and the GSH/GSSG ratio was observed compared to both control and AX-treated cells ( Figure 7A )

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