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Think of it as a clinical investigation, starting with broad hints and gradually narrowing down to the specific evidence needed for a clear diagnosis

While hyperhomocysteinemia may increase the risk of cognitive impairment and age-related neurodegenerative disease (e.g., Alzheimers disease), it is not clear whether vitamin B 12 deficiency contributes to the risk of dementia in the elderly

If response seems inadequate after 4-6 months despite good compliance, consider protocol modifications including combination strategies with complementary peptides or topical additions