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By the time menopause kicked in, Gales was prediabetic and medically obese

Oral Medications: Due to its action on gastric emptying, semaglutide can affect the absorption rate of oral medications

Alongside validated behavioural endpoints such as objective binge frequency and remission, candidate biomarkers include fasting insulin and HOMA-IR, leptin, ghrelin, cortisol, and inflammatory cytokines, plus functional-imaging measures of food-cue reward reactivity and neurocognitive tests of inhibitory control

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However, certain triggers may stimulate melanocytes to produce excess pigment