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2020;15:e0228212

They have shown a further reduction of HbA1c percentage between 0.5 and 0.7 in this combination and in some studies a lower rate of hypoglycaemic events was observed (12, 18, 21, 31)

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12 Patients received once-daily subcutaneous injections of liraglutide 3.0 mg or placebo, as well as counseling on lifestyle modification: at least 150 minutes of physical activity per week, a 500 kcal/day deficit diet, and macronutrient distribution of 30% energy from fat, 20% from protein, and 50% from carbohydrates