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doi: 10.1146/annurev.neuro.22.1.11 202 RudzkiL.MaesM

Chaitep, J

Consequently, GLP-1 RA cessation may precipitate rapid fat regain exceeding lean mass recovery gains, exacerbating sarcopenic obesity risk especially in adults with low initial muscle reserves (Fig

Microdosing refers to starting with smaller, targeted doses of GLP-1 instead of jumping into a full clinical dose

Consider dose reduction if your resting heart rate consistently exceeds 100 BPM, if you experience persistent palpitations or chest discomfort, or if the heart rate increase significantly affects your exercise tolerance