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For years, its role in weight management was less understood, but more recent research suggests GIP receptor activation may enhance the bodys sensitivity to GLP-1, improve fat metabolism, and further support appetite regulation

Geraets AFJ, Khler S, Muzambi R, Schalkwijk CG, Oenema A, Eussen SJPM, et al

They counteract the inability to initiate movement and catalepsy (muscular rigidity and fixed posture regardless of external stimuli), which in turn results in significantly reduced dopaminergic cell activity that is involved in the direct pathway of movement

It is simply an honest assessment of the clinical evidence