Semaglutide (brand names Ozempic , Wegovy ) and tirzepatide ( Mounjaro , Zepbound ) have shown dramatic weight-loss effects in clinical trials and real-world use ( [20] ) ( [21] )
Peptides may be available as FDA-approved drugs or, in certain cases, as compounded preparations under Sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act (FDA, 2021)
Strategies aimed to block the ligandreceptor interaction involve receptor neutralising antibodies (Kalebic et al, 1994)
The estimated background risk of major birth defects and miscarriage for the indicated population is increased when compared to the general population
However, safety assumes proper medical oversight, quality sourcing from licensed pharmacies, appropriate dosing, and monitoring for contraindications