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Expert Opin Drug Saf 17:277292 Acknowledgements Medical writing assistance with the editing of the manuscript was provided by Mimi Chan, PhD, of Springer Healthcare Communications, with funding provided by Kyowa Kirin, Italy

Although lowering of insulin levels with diet or drugs such as metformin and diazoxide seems generally beneficial, some practitioners also utilize strategic elevations of insulin levels in combination with chemotherapeutic drugs

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Evening training partially reverses accumulated insulin resistance, creating a temporary sensitivity window