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No alternatives to PZQ are currently available and few drugs or vaccines are in the clinical pipeline for schistosomiasis treatment 6,7,8

"Adverse drug reactions"

We discovered this in 2007, as you can imagine 2007 it was too far [00:23:00] ahead of the game

As discussed above (in the section Role of mitochondria in synaptic transmission), Ca 2+ signaling is involved in the accumulation of mitochondria at the postsynaptic regions, where these organelles participate in neuronal Ca 2+ buffering and support of neurotransmission [93]