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Unlike many peptides that are synthesized and secreted by endocrine glands, MOTS-c originates directly from the mitochondria, highlighting its intimate connection to cellular energy processes

This dual role, known as antagonistic pleiotropy, beneficially suppresses tumor initiation early in life but detrimentally increases the risk of age-related pathologies, later

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gossypii riboflavin overproduction and determined that exposure of overproducing cells to sunlightmimicking light during growthinduced intracellular ROS and DNA damage accumulation together with a 1.5-fold increase in riboflavin production