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And importantly, clinicians should remain open to considering rare diagnoses like ROHHAD when the phenotype includes hypoventilation, autonomic dysregulation, or extreme hyperphagia. Perhaps one of the most exciting takeaways is that this patients hyperphagia improved markedly (and likewise quickly worsened during medication interruptions), suggesting that some of her hyperphagia was being modulated by GLP-1 RA therapy

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Salazar's explanations seemed to be enough for NOP athletes

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It is characterized by progressive biliary inflammation and fibrosis, often leading to cirrhosis, portal hypertension, and liver failure, with liver transplantation remaining the only life-prolonging treatment for advanced cases 59,60