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Gastrointestinal adverse events were predominantly limited to initial dosing, while dose escalation resulted in lower discontinuation rates owing to these adverse events than among patients who remained on the starting dose

Medicare weight-loss drug copays vary, but the average out-of-pocket cost to obtain GLP-1s through Part D at the end of 2025 was $167 per month and climbing, according to a study by researchers at University of Pennsylvania

Therefore, future studies comparing stroke outcomes based on risk stratification and among drugs pertaining to the same class are necessary

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