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A review of research studies shows that the average duration of B12 injection benefits is around 12 weeks

If neurological involvement is suspected, treatment should be started urgently and must not be delayed whilst awaiting blood test results

Elevated serum B12 is usually asymptomatic and discovered incidentally during routine blood tests Common causes include B12 supplementation, liver disease, haematological disorders, and chronic kidney disease Symptoms such as jaundice, unexplained weight loss, or bruising suggest underlying pathology requiring investigation B12 is water-soluble with no established upper safe limit, and excess is naturally excreted by the kidneys Management focuses on identifying and treating underlying causes rather than lowering B12 levels directly Patients with persistent elevation should undergo comprehensive assessment including liver function, renal function, and haematological investigations Table of Contents What Are the Symptoms of High Vitamin B12 Levels

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Changes in NNMT activity shouldnt be interpreted as producing predictable changes in NAD+ levels across all biological systems