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In yeast, assembly of FeS clusters on Grx4 requires the cytosolic FeS assembly machinery, but it is not dependent on the remaining cytosolic FeS cluster machinery

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In addition, elevated TMAO levels are closely associated with an increased risk of cardiovascular disease in CKD patients, possibly due to TMAO enhancing platelet reactivity and amplifying endothelial inflammatory responses, thereby increasing the risk of thrombosis

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