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TGF- is a central regulator of fibroblast activity and collagen gene expression

The severity of injury or inflammation can affect how long it remains active at the target site

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Although not implemented in practice, pre-clinical studies with xenograft models have given positive responses, with models showing reduced growth in tumours, singly or in combination with therapeutic interventions [148, 150,151,152,153,154], with some exceptions where no benefit was observed [155, 156]

Its the process of taking that freeze-dried ( lyophilized ) powder and carefully dissolving it into the right liquid solvent, turning it into a stable, active, and accurately concentrated solution ready for your experiments