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Each patient undergoes an assessment prior to treatment to ensure suitability and safety

Author Contributions: Conception and design: K.S.H., K.P., R.H., J.Y., H.S.-D., and S.J.C

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Opioids are a family of drugs related to opium, including heroin, fentanyl, morphine, and codeine

Abstract To assess the correlation between endothelial dysfunction and the serum levels of biomarkers of inflammation, remodelling and oxidative stress in essential hypertension, 78 treatment-nave essential hypertensives (mean age 43 years) underwent measurement of endothelial dysfunction, using the maximal acetylcholine-induced forearm vasodilation and serum levels of adhesion molecules, selectins, chemokines, metalloproteinases, copper, zinc, selenium, vitamins, homocysteine, malondialdehyde, erythrocyte glutathione peroxidase and erythrocyte superoxide dismutase