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[1] [17] Whilst UK law permits the prescribing of unlicensed medicines in limited circumstances, practical access to retatrutide is effectively restricted to participation in a registered clinical trial

Certain compounds, when taken orally, undergo significant metabolism in the digestive system and liver before reaching systemic circulation

The North Carolina State Health Plan provides a striking example of the financial implications involved, estimating that continuing to cover brand GLP-1s for weight loss in 2024 would require increasing premiums by $48.50 per subscriber per month for all members, not just GLP-1 users

Globally, AD cases increase every 3 seconds and are expected to reach 139 million by 2050