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Hepatology 70 , 8497 (2019)

Cummings: There are a lot of hints that the drugs may act in the reward centers of the brain, and those actions may have something to do with why they seem to be associated with lower alcohol and substance abuse and smoking, and other compulsive behaviors like gambling and shopping

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Longer and more intense workouts may cause increased gastrointestinal issues, like nausea and stomach discomfort, so trainers focus on consistent, moderately intense workouts