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These findings are based on varied certainty of evidence, which ranged from low to high

For most people, taking 2 grams or less per day is relatively safe and does not cause serious side effects

Vision Loss and NAION Concerns Non-arteritic anterior ischemic optic neuropathy (NAION) has emerged as a particularly devastating injury linked to GLP-1 medications, representing the second leading cause of optic nerve-related blindness in adults

Many people find their best results at doses between 1.0 and 2.4 mg per week, depending on their metabolism and weight loss goals

Weight loss induced by semaglutide can reduce hepatic steatosis (fat accumulation in the liver), decrease liver inflammation, and improve liver enzyme levels in individuals with obesity-related liver disease