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A short non-diabetic cohort measured a flat 2.5 mg dose for about four weeks and found weight and insulin-resistance movement (about -4.7% body weight). That makes "2.5 mg has no data" outdated

Acute and subchronic toxicity studies in rats have not revealed significant toxicity at the therapeutic doses studied

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With seven Mr

By preserving SAM, NNMT inhibition may restore normal epigenetic control of metabolic gene expression in fat cells