Injections can cause minor effects such as irritation or itching at the injection site, and the consumer fact sheet is a good plain-language reference on what B12 does and does not do
Analyses from a study screening for GBA mutations found that GBA carriers were primarily male, had greater occurrences of cognitive dysfunction or dementia, and experienced hallucinations more frequently (not associated with drug treatment) when compared to patients without GBA mutations [28]
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Whether affecting skin, liver, lungs, or nervous system tissue, the underlying mechanism involves similar gene expression changes that promote regeneration and reduce damage accumulation
The implication for clinical practice is that restoring youthful MOTS-c signaling might be a mechanistically legitimate target for longevity intervention