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The researchers note that these problems probably didnt show up in the clinical trials that led to the dugs approval because those studies werent large enough to capture some of these rarer adverse events, or the studies recorded these events as symptoms, rather than delving their underlying causes

Specifically, the MTHFR gene codes for an enzyme called methylenetetrahydrofolate reductase that turns folate into the active form, 5-methyltetrahydrofolate

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These genetic markers don't predict exact medication response, but they may help provide context for your provider about potential responsiveness patterns

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