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Because safety data remains limited, patients should avoid extended cycles unless a qualified provider determines that continued use is appropriate.

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Its foundational description was published by Raun and colleagues in the European Journal of Endocrinology in November 1998, where it carried the developmental code NNC 26-0161

Dan Nayot (humble-brag: hes one of North Americas top reproductive endocrinologists and infertility specialists) led the research team and ensured top-notch data quality