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It is administered once weekly via subcutaneous injection, starting at 2.5 mg and titrated up to 15 mg as tolerated

It is the first approved dual GIP and GLP-1 receptor agonist, which means it activates two separate incretin pathways that single-agonist medications like semaglutide cannot reach

Groc L, Gustafsson B, Hanse E

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Women of childbearing potential should use effective contraception while taking GLP-1 medications, and semaglutide should be discontinued at least 2 months before a planned pregnancy