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These findings align with preclinical data showing that circadian disruption enhances TNBC tumor growth and impairs the time-dependent efficacy of cisplatin therapy, suggesting that both intact circadian signaling and melatonin rhythms are crucial for optimizing chemotherapeutic outcomes 58

While kojic acid is generally considered safer than hydroquinone, pregnant and breastfeeding women should consult their healthcare provider before use

TRANSCRIPTIONAL UP-REGULATION OF NRF2 GENE BY ONCOGENE-DEPENDENT SIGNALING Because the degradation process primarily regulates the level of Nrf2 protein, there have been a few studies concerning the transcriptional control of the Nrf2 gene

However, the lack of long-term human clinical data means some uncertainty remains

What is the recommended storage temperature for GHK-Cu