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Yes, people with certain conditions need special doses

Discovery and Research History (Pickart, 1973Present) Pickart's foundational observation was that plasma from young donors caused liver cells from older donors to behave more like young tissue

(PubMed) Lee IM, Cook NR, Gaziano JM, et al

Safety, and tolerability of brensocatib in participants with non-cystic fibrosis bronchiectasis (ASPEN) [EB/OL]

For example, the Northwest Region cited above says it covers Ozempic for weight management if the patient has a BMI of 30 kg/m2 or more, or if they have a BMI of 27 kg/m2 or more plus diagnosed hypertension, Type 2 diabetes, or hyperlipidemia