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Dose escalation, which is standard practice with most GLP-1 medications, helps to optimise therapeutic effects whilst minimising gastrointestinal side effects

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While depression is often treated with talk therapy or medication, studies are now revealing it also has strong biological underpinnings with evidence-based links to dietary habits

Male and female DIRKO, GLPDRKO, and WT controls were housed for 5 weeks at TN or cold temperatures

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