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In order to determine which isoform of Sec24 is involved in the sorting of SLC7A11, immunoprecipitation (IP) was carried out to test the interaction of SLC7A11 and Sec24 isoforms

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There have been postmarketing reports of renal impairment, acute kidney injury, and worsening of chronic renal failure, which sometimes has required hemodialysis, in patients treated with GLP-1 receptor agonists

Yamamoto Y, Aizawa K, Mieno M, Karamatsu M, Hirano Y, Furui K, Miyashita T, Yamazaki K, Inakuma T, Sato I, Suganuma H