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Cardiomyocyte Survival : GLP-1 signaling can activate pathways within heart muscle cells that reduce apoptosis (programmed cell death) and protect them from injury

Additionally, dietary shifts toward protein-rich foods (common during GLP-1 therapy) can alter skin pH and bacterial flora, occasionally causing localized itching

Stanley TL et al

The You should not use a medication after its expiration date as it can be less effective and have an increased risk of safety issues

High-dose CBD (the pharmaceutical Epidiolex at 20mg/kg/day doses far above consumer wellness use) has been associated with liver enzyme elevations in clinical trials, but this is a dose-level concern not relevant to consumer CBD products