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72 Intracranial pathological changes of microangiopathy include endothelial dysfunction, platelet aggregation impairment, and increased inflammation

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Interestingly, the relatively higher abundance of polysaccharide-degrading taxa such as Prevotella in the duodenum compared to the jejunum and ileum may reflect passive transfer from the rumen rather than indigenous colonization, highlighting the role of the small intestine as a transitional zone in the digestive continuum 73

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DIO2 is largely responsible for the local conversion of T4 to T3 in extrathyroidal target tissues ( Reference Kohrle, Jakob and Contempre 69 )