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This section focusses on the application and related mechanisms of targeting IGFs in cancer therapy

When mast cells misbehave Mast cells are essential in the immune response, but overactive mast cells either too many or triggered too easily can cause a cascade of different symptoms

What works optimally for one person may require adjustment for another

BMC cancer 11 (1), 14413

While significant breakthroughs have been achieved in multimodal modulation of mitochondrial biogenesis, mitophagy, and dynamics, persisting challenges include incomplete elucidation of molecular regulatory networks and genetic foundations, limitations of single-pathway intervention strategies in achieving multi-target coordination, and technical barriers imposed by the selective permeability of the blood-brain barrier (BBB) that hinder clinical translation of mitochondrial-targeted therapies (Meng et al., 2024)