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Mechanism of Action FOXO4-DRI is a D-retro-inverso peptide that interferes with the FOXO4-p53 axis in senescent cells

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From Wikipedia, the free encyclopedia AOD9604 is an orally active, lipolytic 16-amino acid peptide fragment of human growth hormone and derivative of the C-terminal domain of human growth hormone (HGH)

This process is associated with morphological alterations typical for apoptosis, like cell shrinkage, membrane blebbing, and phosphatidylserine (PS) translocation to the outer leaflet of the cell membrane phospholipid bilayer [22, 23]