539546, April 1991, PMID 2007906
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While current redox proteomics in CF often focuses on identifying which proteins are modified (e.g., carbonylated, glutathionylated), techniques like FPOP offer the potential to delve deeper into how these modifications occur - identifying specific residues targeted by ROS - and how these modifications, or the oxidative environment itself, impact protein structure, dynamics, and interactions (Johnson et al., 2019
He delves into how cortisol mobilizes the body for action, with morning sunlight exposure helping stimulate its release
Clinical safety and efficacy of novel antifungal, fosmanogepix, for the treatment of candidemia: results from a Phase 2 trial