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Similarly, magnetic cationic liposomes designed for targeted corticosteroid delivery reduced drug-induced cytotoxicity in hearing loss models by preserving mitochondrial function and reducing cellular senescence (Iftode et al., 2025), while liposome-encapsulated rutin attenuated cisplatin-induced ototoxicity by suppressing p53-associated oxidative injury (Liu et al., 2026)

(ii( conjugation to foreign chemicals to make them more water-soluble, less toxic, and excretable