Tezel G, Hernandez MR, Wax BM
A liposome is not a fixed, stable object: it is a microscopic fat droplet that naturally tends to merge with other liposomes, fall apart, or leak its contents, particularly during storage
Researchers observed that upon binding, IGF-1 LR3 induces IGF-1R autophosphorylation, recruiting IRS-1 (insulin receptor substrate-1) and activating two major downstream cascades: the PI3K/Akt pathway (promoting cell survival, protein synthesis via mTOR, and glucose uptake) and the Ras/MAPK/ERK pathway (promoting cell proliferation and differentiation)
This does not mean your supplement is prohibited
However, the researchers did note significant effects of the combination: We conclude that the choline-induced decrease in serum and urinary carnitine is buffered by carnitine preloading, and these supplements shift tissue partitioning of carnitine that favors fat mobilization, incomplete oxidation of fatty acids and disposal of their carbons in urine as acylcarnitines in humans. Yet, the researchers also used a dose that was much lower than the dose used in the animal studies
