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This work was supported by the National Natural Science Foundation of China (Grant number: 82205114) Research Grant for Health Science and Technology of Pudong Municipal Commission of Health committee of Shanghai (Grant number: PW2022D-15)

Among patients receiving VK2735 in the VENTURE study, the majority (92%) reported drug related TEAEs as mild or moderate in severity

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Glutathione Endogenous tripeptide that detoxifies reactive oxygen species, maintains cellular redox balance, and modulates melanin pathways to support even tone

The evidence is promising, but not yet conclusive for the combination approach