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### Discard the Vial If: - It has been more than 30 days since reconstitution - You see cloudiness, particles, or color changes - The vial was left at room temperature for more than a few hours - You suspect contamination (e.g., the stopper was touched without cleaning) When in doubt, discard and start fresh

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doi: 10.3389/fimmu.2026.1736082 Received 30 October 2025 Revised 06 March 2026 Accepted 09 March 2026 Published 26 March 2026 Volume 17 - 2026 Edited by Christian David Sadik, University of Lbeck, Germany Reviewed by Samanta Celeste Funes, CONICET Multidisciplinary Institute of Biological Research of San Luis (IMIBIO-SL), Argentina Igbayilola Yusuff, Baze University, Nigeria Updates Copyright 2026 Yin, Yan, Pei, Rao, Wu, Xue, Sun and Sheng